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Safety in specific populations: Limited data exists for use in patients with kidney disease, liver disease, or cardiovascular disease
Semaglutide reduces cardiovascular risk factors, such as waist circumference, blood pressure, and lipids
Some people with type 1 diabetes will benefit from GLP-1 RA starts albeit this is prescribed off license currently and based on individual need so unlikely to occur within a group start scenario
CrossRef Aging and Western Diet Synergistically Impair Hepatic Thyroid Hormone Signaling to Promote Metabolic DysfunctionAssociated Steatotic Liver Disease (MASLD) in Mice Xinru Zhang, Madhulika Tripathi, Chun Ting Goh, Chee Seng Chan, Anita Boelen, Paul M
There are multiple ongoing phase III studies to investigate survodutide for treatment of obesity, diabetes, cardiovascular disease, and chronic kidney disease
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