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SS-31 (Elamipretide) SS-31 targets cardiolipin, stabilizing mitochondrial membranes and improving ATP output
Nat Commun 14:3439
Blocking IL-8 or STAT3 disrupts this pathway, reducing the pro-metastatic effects induced by erastin-treated TAMs, thereby identifying the STAT3/IL-8 axis as a potential therapeutic target to counteract erastins unintended enhancement of metastasis in resistant OC cells (179)
One heavy session can delay soft-tissue healing by 5-7 days based on inflammatory marker recovery times (Koyuncu et al., 2025)
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