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This system releases ethyl caffeate (EC) and 4-hydroxybenzyl alcohol (HBA) in response to ROS at the IRI site, synergistically scavenging ROS, alleviating mitochondrial oxidative damage, restoring energy metabolism, inhibiting apoptosis and inflammatory responses, and significantly improving renal function and structural integrity [67]
Rarely reported symptoms may include mild skin reactions, gastrointestinal disturbance, or headache, typically following high-dose intramuscular injections
A higher level of active GSH compared with GSSG generally indicates stronger antioxidant protection and a healthier cellular environment
Most reconstituted peptides remain stable for two to four weeks under optimal refrigeration at 2-8C