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Experimental studies indicate that GLP-1 signaling can enhance genioglossus muscle tone, thereby reducing susceptibility to airway collapse during sleep (38, 39)

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The alterations of the mesenchymal cell compartment were also shown to influence their supporting function for hematopoiesis

For tirzepatide at the highest dose, the SURMOUNT-1 trial showed an average of 22.5% weight loss at 72 weeks, which represents one of the most significant weight loss results ever achieved with any medication

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