Pharmacological determinants in GLP-1RA-Associated cancer risk Differential cancer risk profiles across GLP-1RA subtypes and dosing regimens Existing studies underscore significant differences in the effect of various GLP-1RAs on the risk of specific cancers, such as pancreatic cancer [6,7,8, 26, 27]
The GLP-1 receptor agonist exenatide ameliorates neuroinflammation, locomotor activity, and anxiety-like behavior in mice with diet-induced obesity through the modulation of microglial M2 polarization and downregulation of SR-A4
The side effects are its biggest limitation
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