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Atherosclerosis, inflammation and the accumulation of lipids in the inner layer of blood vessel walls lead to vascular blockage and contributes to the development of coronary heart disease, cerebrovascular disease and peripheral arterial vascular disease, and is associated with significant clinical morbidity and mortality rates (57)

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Adverse Reactions in a Clinical Trial with Empagliflozin (Add-On Combination Therapy with Metformin HCl and Sulfonylurea) for Glycemic Control in Adults with Type 2 Diabetes Mellitus In a 24-week placebo-controlled trial of empagliflozin 10 mg or 25 mg administered once daily added to metformin HCl and sulfonylurea, adverse reactions reported in 5% of empagliflozin-treated patients and more commonly than in placebo-treated patients are presented in Table 1 (see also Table 4)

Glutathione is an extremely important cellular protectant, which works alongside a host of other antioxidants to protect against cellular damage and support brain function

Current Chemical Biology 8(2):89-99. [doi.org]