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Published veterinary research on the peptide contributed to understanding of its mechanisms and safety profile, though this animal data has not been directly replicated in human clinical trials

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Dysfunction of CI is a defining feature of circadian disruption and diet-induced obesity in adipose tissue, linking clock misalignment to visceral adipocyte hypertrophy, ectopic lipid deposition in liver and impaired glucose tolerance

Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region

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