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Patients with ongoing injury history or who are returning to training after a setback may benefit from evaluation for combination therapy

[19] This receptor activation leads to inhibition of adenylyl cyclase activity, resulting in decreased cyclic adenosine monophosphate levels and subsequent modulation of protein kinase A activity

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These reactions are usually mild and include: Redness Swelling Itching Tenderness These symptoms generally resolve on their own within a few days