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Phase I and Phase II Detoxification Pathways Phase I metabolism involves cytochrome P450 enzymes that hydroxylate estrogen, creating metabolites including 2-hydroxyestrone, 4-hydroxyestrone, and 16-alpha-hydroxyestrone
S.WangH.et al (2019)
10.1021/acschemneuro.4c00620 65 LiangD.FengY.ZandkarimiF.WangH.ZhangZ.KimJ.et al (2023)
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However, certain groups should reconsider or avoid copper peptides like GHK-Cu, including: Also, while research suggests potential benefits, individual results vary and outcomes cannot be guaranteed
