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In summary, different GLP-1RAs improve skeletal muscle atrophy through multiple molecular mechanisms, involving multiple pathways such as insulin resistance regulation, inflammation suppression, and mitochondrial function improvement (see Table 1), providing a theoretical basis for the clinical treatment of sarcopenia with GLP-1RAs

He stopped his research, though, when his biotech firm foundered

10.3390/biomedicines13010018 24 De RosaS

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Drugs like semaglutide and tirzepatide are reshaping the management of obesity and cardiometabolic disease, with millions of patients now using them for sustained weight loss and risk reduction