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Diabetes, Obesity and Metabolism , 22(9), 1454-1467

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This leads to more LDL cholesterol being removed from your bloodstream ( Diabetes, high blood sugar levels, and obesity are also major risk factors for heart disease, and this supplement seems to help improve all of these conditions ( Given the beneficial effects on all these risk factors, it seems likely that berberine could reduce the risk of heart disease, though more research is needed