"Association of biochemical B 1 2 deficiency with metformin therapy and vitamin B 1 2 supplements: the National Health and Nutrition Examination Survey, 19992006"
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Early studies showed that growth hormone did not directly stimulate the incorporation of sulfate into cartilage, but rather acted through a serum factor, termed 'sulfation factor,' which later became known as 'somatomedin'
Many studies have confirmed oxidant-antioxidant imbalance in migraine, including NO, malondialdehyde (MDA), thiobarbituric acid reactive substances, thiol, catalase, superoxide dismutase, and glutathione imbalances (141, 142)
Wang, L., et al