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Furthermore, retatrutide substantially lowered fasting plasma triglycerides and low-density lipoprotein (LDL)-cholesterol levels in subjects with obesity [57], while in patients with T2DM, it led to a greater reduction in triglycerides compared to dulaglutide and placebo [40]
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This trend toward more extreme obesity categories presents particular challenges for healthcare systems and emphasizes the need for effective interventions ^30
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