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Amifostine is FDA approved for the reduction of cumulative kidney toxicity from repeated cisplatin administration in patients with advanced ovarian cancer and non-small cell lung cancer (Ethyol 1999)

Cisplatin, doxorubicin, and cyclophosphamide are agents known to cause CINV (Janelsins 2013)

These can include rapid heartbeat, chest pain, confusion, muscle cramps and weakness, hives, skin rashes, and difficulty breathing or swallowing [1]

A "yes" to any one ends it

In summary, this review provides a comprehensive overview of the latest trends and technological developments in acute mountain sickness prediction research while explicitly identifying key areas for future attention and resolution