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Gemcitabine + ATR inhibitor regimen generated by DeepChem achieved an objective responRegarding the latest se rate (ORR) of 38% in platinum resistant bladder cancer, which is 2 times higher than the traditional regimen

As for nephroprotection, an RCT on the use of febuxostat vs topiroxostat show none improvement in urinary protein/creatinine ratio

A recent case report suggests that such medications can influence brain regions involved in emotional regulation and potentially trigger or worsen severe depressive symptoms

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