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Blood 106:641-649, 2005

However, excess exposure to ROS can lead to pathological damage to human spermatozoa curtailing their competence for fertilization and disrupting their genetic integrity

Interferon is a molecule that leads the immune response against viral infections

Further, NRF1 has been shown to be important for the survival of hepatocytes and to mediate oxidative stress during development 62,63

In vivo treatment with the Mel-C/L NPs significantly reduced paw edema, pain sensitivity, myeloperoxidase, metalloproteinase-9, TNF-, IL-1, malondialdehyde, and nitric oxide while elevating levels of antioxidants glutathione reduced and catalase