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Despite the potential benefits of GLP-1RAs, several challenges hinder their implementation in managing WR after bariatric surgery [15, 16]
They are real and happening now
no hepatic safety signal has been observed across the orforglipron clinical program, distinguishing it from the discontinued Pfizer oral GLP-1 candidates lotiglipron and danuglipron, both of which were terminated due to liver toxicity concerns
These popular drugs, used to treat diabetes and obesity, help promote weight loss by reducing appetite and food intake
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