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GE2 treatment also led to a significant reduction in the levels of the chemokine CXCL1 compared to vehicle (main effect of treatment: F (1,45) = 7.319, p 2 = 0.140, p = 0.010

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GLP-1RA drugs reduce total caloric intake by roughly 16 to 39 percent, and while most of the resulting weight loss is fat, a smaller but consistent share is lean tissue, commonly cited in the range of about 25 to 40 percent of weight lost, with some analyses citing higher figures where loss is rapid and unmanaged [1, 2]

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