Other factors include too low of a dose, poor individual response, poor diet, too much stress, not being on long enough, poor sleep schedule, using drugs or alcohol, not following the dosing protocol, and not drinking enough water
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[26] [27] Never discontinue therapy without medical guidance, as abrupt cessation can lead to loss of glycemic control or weight regain
Why tirzepatide works when semaglutide doesn't: the two-receptor difference The core reason comes down to how many hormone systems each drug engages
1.5-2mg : Noticeable appetite reduction, early fat loss visible on the scale