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At the highest dose of 12 mg, participants with type 2 diabetes achieved a mean body weight reduction of approximately 16.9% from baseline at 24 weeks
JAMA Netw Open 7(6):e2416775 Mabilleau G, Mieczkowska A, Chappard D (2014) Use of glucagon-like peptide-1 receptor agonists and bone fractures: a meta-analysis of randomized clinical trials
Tsilou ET, Rubin BI, Reed G, Caruso RC, Iwata F, Balog J, Gahl WA, Kaiser-Kupfer MI (2006) Nephropathic cystinosis: posterior segment manifestations and effects of cysteamine therapy
The finding raises questions about whether oral and injectable GLP-1 therapies may have meaningfully different modes of action beyond their delivery format
The body must either excrete these minerals or redistribute them, a process that can temporarily mask deficiency before it becomes apparent
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