Some clients alternate between the two, and others maintain a consistent schedule with one or the other
doi:10.3325/cmj.2012.53.535 Ebert EC
Vitamin B12 Medicine Interactions Chloramphenicol: bacteriostatic antibiotic can interfere with red blood cell response to supplemental Vit B12 Proton pump inhibitors: omeprazole and lansoprazole, etc., slow gastric acid release and may interfere with VIt B12 absorption from food H2-receptor antagonists: cimetidine, famotidine and ranitidine slow the release of hydrochloric acid into the stomach and interfere with Vitamin B12 absorption from food Metformin: might reduce absorption of Vitamin B12 due to altered intestinal motility, increased bacterial overgrowth, etc
However, the reported side effects in humans are almost entirely anecdotal , drawn from user forums, clinician case observations, and biohacking communities rather than controlled trials
Riyazuddin R, Bela K, Horvth E, Rig G, Gall A, Szabados L, Fehr A, Csiszr J (2019) Overexpression of the Arabidopsis glutathione peroxidase-like 5 gene (AtGPXL5) resulted in altered plant development and redox status