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Another recently completed phase 3 clinical trial called REDEFINE 2 , which included 1,207 adults with type 2 diabetes and overweight or obesity, found that after 68 weeks, CagriSema led to weight loss of almost 16% experts say the highest yet in the type 2 population, compared to other weight management drugs like tirzepatide (Mounjaro for diabetes, Zepbound for weight loss) and semaglutide
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Gastrointestinal symptoms during dose changes Nausea, constipation, and other GI symptoms are the most common side effects of GLP-1 therapy, and they tend to re-emerge whenever dosing changes occur
Biochem Pharmacol 1 PubMed Hata M, Sasaki E, Ota M, et al
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