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APR-246 exhibits anti-leukemic activity and synergism with conventional chemotherapeutic drugs in acute myeloid leukemia cells
Targeting enteric release of therapeutic peptides by encapsulation in complex coacervated matrix microparticles by spray drying
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Activation of protective metabolic axes emphasizes the concept of counteracting inflammation through metabolic homeostasis. The IRG1/itaconate axis forms an endogenous negative feedback mechanism in inflammation-activated macrophages, with itaconate and its derivatives suppressing excessive inflammation while enhancing antioxidant responses
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