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This GLP-1R-mediated modulation of transport activity likely represents the molecular coupling between GLP-1R inhibition and the observed Ex9-39-induced reduction in CSF secretion, via reduced cAMP-dependent protein kinase A-mediated phosphorylation of NKCC1 and the Na + /K + -ATPase, and thus lowered activity of these proteins [51,52,53]

GhaithAKJohnsonSEEl-HajjVGAkinduroOOGhanemMDe BiaseGet alSurgical management of malignant melanotic nerve sheath tumors: an institutional experience and systematic review of the literature