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One prevailing theory is that tirzepatide is an imbalanced and biased GLP-1 RA with very low efficacy for recruitment of -arrestin, whilst is acting as an unbiased GIP agonist with full efficacy for -arrestin recruitment [51, 52]

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Its stimulant-free mechanism reduces the risk of anxiety or cardiovascular stress, making it suitable for a broader range of patient profiles , including those with type 2 diabetes or metabolic syndrome

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We are currently in an internal evaluation phase, reviewing the published research and running a structured internal protocol with our clinical team