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doi: 10.3390/biom15010046
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Novo Nordisk said it is not currently conducting any clinical studies to evaluate semaglutide in patients with substance-use disorders or addiction-related illnesses, although changes in alcohol consumption is a secondary goal of a trial it is conducting of semaglutide in combination with other medicines in patients with alcohol-related liver disease
Today, most people think of semaglutide as a weight-loss medication, but it was actually developed for another purpose: to help manage Type 2 diabetes
A multifunctional poly(amino acid) nanomedicine (PM-DPA/R848) has been developed that encapsulates the TLR7/8 agonist resiquimod (R848) within a nanocarrier composed of poly(L-methionine) and alendronate-functionalized DSPE-PEG ( Calcium carbonate (CaCO3)-based nanosystems have been engineered to simultaneously neutralize the acidic TME and reprogram TAM polarization
