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A375 cells were cultured until 3050% confluence, then treated with a complete growth medium containing 0.1 M doxorubicin (Sigma D1515)

Support wound healing, antioxidant activity, and skin barrier repair through its effects on fibroblasts and glycosaminoglycan production

Verification: Ex vivo and in vitro studies show GHK-Cu has an exceptionally high affinity for copper

Furthermore, peptides of soy protein, rice protein, and hydrolysate of wheat gliadin derived from wheat (Teschemacher, 2003) have opioid activity and can cause an increase in the antioxidant and methylation capacity of nerve cells (Trivedi et al., 2014) and lower the NO level across the cellular environment (Yin et al., 2015)

Decrease dose if: Experiencing consistent side effects (headaches, fatigue, GI disturbance), achieving satisfactory results at current dose with no need for escalation, or cost considerations favor using minimum effective dose