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These advances underscore the potential of gene-based interventions to transform the management of HF, offering hope for durable improvements in cardiac function
Paradoxically, PFKFB3 expression is reported to correlate with pro-invasive and pro-inflammatory activity in rheumatoid arthritis patients (218, 219), while selective inhibition of endothelial PFKFB3 reduces polarization of M2 macrophages (189)
doi: 10.2337/db14-0849 151 van GalenK
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