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For example, VSL#3 seems to be effective not only in pouchitis, but also in mild to moderate UC not responding to conventional therapy [187]
It is most useful when a conventional treatment path has been followed and has plateaued
The mechanisms of probiotic effects in IBD is unclear at present, but might involve direct anti-inflammatory effects, e.g
The liver stores substantial quantities of vitamin B12, and hepatocellular damagefrom conditions such as cirrhosis, hepatitis, or hepatocellular carcinomacan release these stores into the bloodstream
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