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A loading phase of 1mg three times weekly for two weeks, then maintenance of 1mg every two to three months, adjusted for the cause and any neurological involvement
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The number of animals assigned per condition was selected to account for the variability of the examined phenotypes based on pilot experiment and past experience with the animal models (6 animals per experimental condition)
doi: 10.1152/physrev.00014.2015 48
Schizophrenia, on the other hand may be linked to excessive synaptic pruning within the prefrontal cortical brain circuitry (Sekar et al., 2016
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