However, more people experienced negative gastrointestinal side effects when receiving the higher dose (34% compared to 30.8%)
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That familiarity hides a cost: when dosing, meal timing, side effects, menstrual patterns, and medication changes all overlap, signals get buried, and it becomes hard to tell cause from coincidence
These benefits were evident beginning at week 4 and persisted throughout the duration of the studies
Most side effects are gastrointestinal and tend to be mild to moderate, often occurring when the dose is increased