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As rehabilitation progresses and active training resumes (typically 8-12 weeks post-surgery depending on the procedure), the protocol transitions to maintenance dosing with cryotherapy reserved for higher-intensity training days

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Li F, Jiang T, Li Q, Ling X (2017) Camptothecin (CPT) and its derivatives are known to target topoisomerase I (Top1) as their mechanism of action, did we miss something in CPT analogue molecular targets for treating human disease such as cancer

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