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& Zina, G
While TIR offers a slight improvement in these adverse effects, its co-administration with DXN does not significantly counteract them
It also integrates effectively with peptide systems and soothing actives
Class NNMT Inhibitor (Nicotinamide N-methyltransferase) Molecular Weight 193.2 Da (small molecule) Half-life Under investigation Purity 98% (HPLC) Form Powder Storage 20C, dry, protected from moisture Reconstitution DMSO or sterile water (partial solubility) Mechanism of action 5-Amino-1-methylquinolinium (5-Amino-1MQ) is a competitive inhibitor of NNMT an enzyme overexpressed in adipose tissue in obesity that converts nicotinamide to 1-methylnicotinamide while consuming SAM (S-adenosyl methionine)
Its safety is supported by its natural presence in the body and homeostatic regulation, which prevents copper toxicity (Pickart, 2010)
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