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Genetic polymorphism of the human manganese superoxide dismutase: what difference does it make
Additionally, natural small molecules such as tea polyphenols exhibit iron-chelating properties, although careful dosing is required to avoid hepatotoxicity (309)
Second, hyperhomocysteinemia detected only by the oral methionine-loading test (approximately 27% of patients), which might mainly result from an inhibition of the transsulfuration pathway (vitamin B 6 deficiency or heterozygous CBS defect), and which increases the risk 1.5-fold
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