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Because of a lapsed administrative patent filing by Novo Nordisk, generic manufacturers like Sandoz have already filed for approval

Current evidence from large-scale randomized controlled trials, observational studies, and real-world data presents a complex picture of this relationship

Glutamate taken up by perisynaptic astrocytes is then converted to glutamine via glutamine synthetase (Niciu et al., 2012)

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Patients with a history of inflammatory bowel disease, irritable bowel syndrome, or previous gastrointestinal surgery may be at higher risk of experiencing more pronounced digestive symptoms and should maintain closer contact with their healthcare team