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Mice that overexpress Jak2VF in their erythroid lineage (VFEpoR mice) exhibit heightened necrosis in atherosclerotic plaque and erythrocytic ferroptosis, and VFEpoR increases erythrocyte lipid hydroperoxide and decreases antioxidant defense ability

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Reviewing statin therapy, which should be stopped before conception Starting low-dose aspirin (75150 mg daily) from 12 weeks' gestation to reduce pre-eclampsia risk in women at high risk, including those with pre-existing diabetes Women should never adjust or stop medications without consulting their diabetes team, as both hyperglycaemia and abrupt medication changes carry significant risks

No, both medications should be avoided in pregnancy