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Bananas are a nutritious whole food providing essential vitamins, minerals, and dietary fibre

Unlike pharmaceutical sleep aids that cause next-day drowsiness, cognitive impairment, tolerance, and dependency, DSIP enhances sleep quality without sedative side effects, maintains normal sleep architecture, causes no morning grogginess, develops no tolerance requiring dose escalation, and demonstrates no withdrawal symptoms or addiction potential

In 1993, the first small-molecule ligands, L-692,429 and its superior derivative, L-163,191 (MK-0677), were developed, further accelerating research in this field (Table 1) (Smith et al., 1993

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As that demand has risen, different peptide formats have become available from topical creams and oral tablets to injections, which are often used for therapeutic purposes due to their high bioavailability