The 2025 study by Anna Ferrulli, Livio Luzi, and colleagues (published in Obesity) is a retrospective comparison of three treatments in patients with obesity and type 2 diabetes (T2D): repetitive transcranial magnetic stimulation (rTMS) using an H-ADD coil targeting bilateral prefrontal cortex (PFC) and insula, semaglutide (at a modest 0.5 mg/week dose), and SGLT2 inhibitors
Mounjaro works slightly differently because it targets both GLP-1 and GIP receptors
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Avoid these combinations
The FDA has been tracking adverse events tied specifically to compounded not branded GLP-1 products