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All mice were housed under specific pathogen-free (SPF) conditions with 12 h light/12 h dark cycle at 2124 C, and humidity at 4060%, and were fed with a standard chow diet at the Laboratory Animal Center of the Sixth Affiliated Hospital, Sun Yat-sen University

This multi-target intracellular signalling profile accounts for its consistent positive results across tendon, ligament, muscle, bone, skin, and gastrointestinal tissue repair models in the published literature