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The following sources give you the unfiltered picture - clinical evidence, regulatory context, and safety data straight from the organizations that publish it: FDA.gov - official FDA communications on compounded semaglutide, tirzepatide, and the 503B Bulks List proposal (April 30, 2026)
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Sevarino, 2022)
A landmark clinical trial of semaglutide, published in 2021, found that participants experienced an average of 15% weight loss over the course of 68 weeks while those on placebo lost 2%
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