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Endogenous GLP-1 affects postprandial blood glucose by slowing gastric emptying and glucose absorption in healthy subjects (Deane et al., 2010) by inhibiting antral and duodenal motility and stimulating pyloric motility (Schirra et al., 2006)

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J Nutr.Biochem

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This finding ultimately led to the development of bremelanotide (Vyleesi), approved by the FDA in 2019 for hypoactive sexual desire disorder (HSDD) in premenopausal women