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Figure 6 presents the simulated fate of a single 50 M doxorubicin exposure (top panel), as well as the subsequent O 2 . and H 2 O 2 profiles, over a 30-minute time-span
Besides, by upregulating the cytochrome c oxidase 2 (SCO2) (167), TP53 initiates several transcriptional programs to promote the expression of genes related to mitochondrial biogenesis (168), such as apoptosis-inducing factor (AIF) (169, 170) and ferredoxin reductase (FDXR) (171)
9 Nausea that is not following the expected pattern
The specific risks identified in animal models include potential effects on pancreatic development and metabolic organ formation during critical windows of fetal growth
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