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This is a single rabbit study, not human evidence
Chang CH1, Tsai WC2, Hsu YH3, Pang JH4
Allelic exchange substrates (AES) containing the Kan R flanked by ~1 kb identity arms for site-specific recombination were obtained by high fidelity PCR using BAC Rv412- cobM,K ::Kan R as template and Conf-KO BAC cobMK-Fw/Conf-KO BAC cobMK-Rv primers
The synthetic origin ensures batch-to-batch consistency crucial for reproducible research
The CDC notes that it does not affect viruses and does not provide complete protection against bacterial contamination
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