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It was the most effective antidiabetic agent anyone had ever seen, says Andrew Young, former vice president of research at Amylin Pharmaceuticals, the San Diegobased company that brought Byetta to market

Statistical inference for fixed effects used Satterthwaites approximation of degrees of freedom (lmerTest v.3.1.3) and FDR correction (BenjaminiHochberg) was applied across metabolites separately for each fixed-effects term

The convergence of oral bioavailability and multi-receptor agonism is redefining the landscape of obesity and diabetes therapeutics

One potential explanation is group heterogeneity, in this case an inclusion of participants with different biological backgrounds despite similar clinical presentations, which might lead to a decrease in power to detect changes, especially if these are subtle

444 T-cell exhaustion has also emerged as a cross-cutting resistance signature that compromises the response to ICIs across multiple tumor types