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The structure, organization and differential expression of the gene encoding rat heme oxygenase-2

The mesolimbic system, which includes brain regions such as the ventral tegmental area and nucleus accumbens, plays a central role in motivation and reinforcement

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In a Phase 2 obesity trial of retatrutide published in the New England Journal of Medicine in 2023, nausea, diarrhea, vomiting and constipation were cited as the most common adverse events, with higher doses associated with more severe problems