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At the phylum level, the top 15 taxa by relative abundance were selected for the stacked bar plot (Figure 14A), revealing that gut microbiota across groups primarily consisted of Firmicutes , Bacteroidota , Desulfobacterota , and Proteobacteria
This pathway activation enables: Enhanced neuronal survival under stress conditions Increased dendritic arborization and synaptic density Improved axonal sprouting and regeneration Activation of neuronal repair mechanisms Studies using neuronal cell cultures revealed that Cerebrolysin significantly increases neurite outgrowth and protects against excitotoxic injury, effects attributed to neurotrophic factor-like activities[2]
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Serum metabolomics reveals the intervention mechanism and compatible regularity of Chaihu Shu Gan San on chronic unpredictable mild stress-induced depression rat model