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Description

Messenger-RNA changes generally require longer observation periods, while tissue remodeling and altered depot mass may require still longer experiments

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Filomeni et al., 2011

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25(OH)VD, insulin, glucose, GSH, protein carbonyl, and Malondialdehyde (MDA) assays Plasma levels of 25(OH)vitamin D were determined using an ELISA kit (Calbiotech, Spring Valley, CA), levels of insulin were determined using ELISA kits from ALPCO Diagnostics (Salem, NH)

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Both compounds have approximately 7-day half-lives, which makes a combined once-weekly research protocol pharmacokinetically practical

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Genetic polymorphisms may be a contributing factor as to why its hard to precisely pin down a healthy MMA threshold

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