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Several studies suggest that inflammation may contribute to depression by affecting the function of neuronal mitochondria in the brain [20]
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APOS Trends Orthod 5(5):181181 Vay L, Gu C, McNaughton PA (2012) The thermo-TRP ion channel family: properties and therapeutic implications
Given that active demethylation occurs on numerous neighboring CGs, as shown during electro-convulsive treatment-induced neurogenesis in adult hippocampus (Ma et al., 2009b), the removal of their methylation through the repair machinery would involve extensive damage to DNA and thus might represent a costly mechanism (Szyf, 2009)
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