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Differential Diagnosis Pigmented lesions, which are common in the mouth, may be of endogenous or exogenous origin
With less saliva, bacteria can multiply, leading to bad breath, gum disease, or tooth decay over time
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Simultaneously, the combinatorial treatment also showed a significant decrease in the mRNA expressions of pro-inflammatory genes ( TNF- , IL-2 , INF- , TGF- , and VEGF ) known to be involved in the proliferation of cancer cells
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