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While the overall risk of pancreatitis and pancreatic cancer with semaglutide use appears low based on available data, clinicians should remain vigilant in monitoring patients for signs and symptoms of pancreatic dysfunction, including persistent abdominal pain, nausea, vomiting, and elevated pancreatic enzyme levels

Common side effects include nausea, bloating, and mild gastrointestinal discomfort, especially during the first few weeks

doi: 10.1056/NEJMoa1607141 43 MarsoS

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Researchers estimated that semaglutide could cut the obesity prevalence in the United States by about 46% and prevent more than 1.5 million CVD events over 10 years when given to eligible patients with overweight or obesity